Palladium-catalyzed synthesis of N-vinyl pyrroles and indoles.
نویسندگان
چکیده
A stereospecific palladium-catalyzed N-vinylation of azaheterocycles with vinyl triflates is described. Cyclic and acyclic vinyl triflates along with nonnucleophilic azaheterocycles were found to be substrates for this palladium-catalyzed synthesis of N-vinyl pyrrole and indole derivatives.
منابع مشابه
Formal aromaticity transfer for palladium-catalyzed coupling between phenols and pyrrolidines/indolines† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02578e Click here for additional data file.
We herein describe a palladium-catalyzed formal aromaticity transfer coupling reaction between phenols and pyrrolidines or indolines to generate the corresponding N-cyclohexyl pyrroles or indoles. In this transformation, the aromaticity of phenols is formally passed on to the pyrrolidine or indoline units. Substituted phenols thus can serve as latent cyclohexyl equivalents for the fast construc...
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 70 21 شماره
صفحات -
تاریخ انتشار 2005